OPRINS JUDITH,PARREN PAUL,BAADSGAARD OLE,GRAUS YVO,LISBY STEEN,WINKEL JAN VAN DE,WEERS MICHEL DE,VAN VUGT MARTINE
申请号：
NZ61194707
公开号：
NZ611947A
申请日:
2007.09.26
申请国别(地区):
NZ
年份:
2015
代理人:
摘要：
Discloses a therapeutic composition comprising a non-agonistic antibody which binds to CD38, at least one corticosteroid, and at least one non-corticosteroid chemotherapeutic agent. Also disclosed is the use of a non-agonistic antibody which binds CD38, at least one corticosteroid and at least one non-corticosteroid, in the manufacture of a medicament for the treatment of a patient with cancer involving cells expressing CD38, with a dosing regime comprising at least one dosing cycle that is designed to provide the effective delivery of the medicament over 4 weeks, wherein the dosing cycle is repeated for as long as necessary to achieve the desired biological response in the patient.
