a compound of formula / or a pharmaceutically acceptable salt or prodrug thereof； compound； pharmaceutical composition； method of treating a quinurenine 3-monooxygenase activity-mediated disorder or disorder in an individual in need of such treatment
CELIA DOMINGUEZ,LETICIA M. TOLEDO-SHERMAN,MICHAEL PRIME,NAOMI WENT,PETER JOHNSON,WILLIAM LEONARD MITCHELL
申请号：
BR112014024693
公开号：
BR112014024693A2
申请日:
2013.03.13
申请国别(地区):
BR
年份:
2017
代理人:
摘要：
Certain compounds, or pharmaceutically acceptable salts or prodrugs thereof, pharmaceutical compositions comprising the same and methods of treating patients suffering from certain diseases and disorders response to the inhibition of KMO activity are described, which comprise administering to such patients an amount of at least one compound, or pharmaceutically acceptable salt or prodrug thereof described herein, effective to reduce signs or symptoms of the disease or disorder. These diseases include neurodegenerative disorders such as Huntington's disease.
