A method of treating muscle cramps and muscle pain, and to relieve swelling in and around muscles after strenuous physical activity is provided, whereby an aqueous composition is applied topically to the skin overlying the affected muscles, the composition has dissolved, suspended or dispersed therein (a) an anti-inflammatory agent； (b) an agent that stimulates or promotes cell growth； and (c) an agent that enhances or stimulates the skin's immune system, wherein components (a), (b) and (c) are different.
