Yu, Dong,Wang, Daqing,Putta, Mallikarjuna Reddy,Li, Yukui,Kandimalla, Ekambar R.,Agrawal, Sudhir,Lan, Tao
申请号:
AU2007235231
公开号:
AU2007235231B2
申请日:
2007.04.06
申请国别(地区):
AU
年份:
2012
代理人:
摘要:
The invention relates to the therapeutic use of stabilized oligoribonucleotides as immune modulatory agents for immune therapy applications. Specifically, the invention provides RNA based oligoribonucleotides with improved nuclease and RNase stability and that have immune modulatory activity through TLR7 and/or TLR8.