Described herein are implantable devices, delivery systems and surgical methods for creating a barrier that may be deployed into a digestive system organ to block the biochemical and/or neurohormonal systems thereby providing therapeutic benefit ideally treating diabetes mellitus and obesity. The device for creating a barrier in the digestive system organ may include a wall or conduit whether impermeable or porous at varying degrees. Method of surgical delivery for the device described herein may be conducted through open, laparoscopic, minimally invasive, or endoscopic means. The device may be temporarily secured on a novel delivery system enabling the methods described. The device may be secured to the digestive organ allowing natural biomechanical motion (peristaltic motion) of the digestive system without untoward effects.