BARMAN, Shikha P.,LIU, Moli,BARMAN, Koushik,WARD, Kevin L.,HACKETT, Brendan
申请号:
EP15838075
公开号:
EP3188688A4
申请日:
2015.09.08
申请国别(地区):
EP
年份:
2018
代理人:
摘要:
A nanostructured biocompatible wafer for drug delivery to a tissue. The wafer contains a tissue-reactive mucoadhesive polymer and a mesh formed of a plurality of polymer fibers. Also provided is a method for treating an ocular surface disease, disorder, or infection using the nanostructured biocompatible wafer. Additionally, an injectable sustained-release formulation for treating an ocular disorder is disclosed. The formulation includes a drug contained within a plurality of microparticles formed of a biodegradable polymer and are coated with a tissue-reactive compound. Further provided is a method for treating an ocular disorder by injecting the microparticulate sustained release formulation.