Campbell, Carey V.,Cleek, Robert L.,Crandall, Daniel L.,Davidson, James F.,Drumheller, Paul D.,Hartman, Cody L.,Holland, Theresa A.,Kranzler, Thane L.,Li, Mei,Lostracco, Gregory,Steinhaus, Bruce M.,Tr
申请号：
AU2012337336
公开号：
AU2012337336B2
申请日:
2012.09.05
申请国别(地区):
AU
年份:
2015
代理人:
摘要：
The invention is directed to eluting medical devices that enable consistent "on-demand" delivery of therapeutic agents to a vessel. The medical device of the current invention comprises an expandable member, a hydrophilic coating comprising at least one therapeutic agent about the expandable member or structural layer and an outer sheath with a variably permeable microstructure. The design and methods disclosed herein ensures that therapeutic agent delivery occurs essentially only during expansion of the expandable member, minimizing coating and/or therapeutic agent loss to the bloodstream and providing controlled delivery to the treatment site.
