PROCESSES FOR THE PREPARATION OF GALNAC ACID DERIVATIVES

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专利权人:

Hoffmann-La Roche Inc.

发明人:

Joerg Lill,Rene Trussardi

申请号：

US15890181

公开号：

US20180162894A1

申请日:

2018.02.06

申请国别(地区):

US

年份:

2018

代理人:

摘要：

The invention comprises a new process for the preparation of GalNAc derivatives of the formula Iwherein n is an integer between 0 and 10 and its salts, corresponding enantiomers and/or optical isomers thereof. The GalNAc acid derivative of formula I can be used for the preparation of therapeutically valuable GalNAc oligonucleotide conjugates.

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