LINHAGENS CELULARES DERIVADAS DE MDCK ADAPTADAS PARA CULTURA EM MEIO DE CULTURA ISENTO DE SORO E CULTURA EM SUSPENSÃO E MÉTODO PARA PREPARAÇÃO DE UM VÍRUS VACÍNICO COM A UTILIZAÇÃO DAS CÉLULAS
BONG-YONG LEE,YONG WOOK PARK,KUN SE LEE,MAHNHOON PARK,HUN KIM,YUN-HEE KIM,SU-JEEN LEE
申请号：
PT11823761
公开号：
PT2614140T
申请日:
2011.09.06
申请国别(地区):
PT
年份:
2018
代理人:
摘要：
Disclosed is a Madin-Darby canine kidney (MDCK)-derived cell line. The MDCK-derived cell line is derived from MDCK cells deposited under accession number ATCC CCL-34. The MDCK-derived cell line can be prepared by serum-free culture and suspension culture. Preferably, the MDCK-derived cell line has low or no tumorigenicity. The MDCK-derived cell line is preferably selected from MDCK Sky1023, MDCK Sky10234 and MDCK Sky3851. Further disclosed are a culture method for growing the MDCK-derived cells and a method for producing a vaccine virus using the MDCK-derived cells.
