A method for activating metabolism for muscle cells involves administering an energy-metabolic activating agent to a human patient, the energy-metabolic activing agent as follows:(1) a sugar transporter (GLUT4) gene-expression promoting agent, including at least one active substance selected from the following: 5-hydroxy-3,7-dimethoxyflavone; techtochrysin; 3,7,4′;-trimethylkaempferol; retusine; pentamethyiquercetin; trimethylapigenin; tetramethylkaempferol; and 5, 7-dimethoxyflavone,(2) a sugar transporter (GLUT4) gene-expression promoting agent, including at least one active substance selected from either techtochrysin or 5,7-dimethoxyflavone, and(3) a sugar transporter (GLUT4) gene-expression promoting agent within the muscle cells that includes any one of the chemical compounds shown in the following chemical formula 1. (Of such formula 1, R1 and R2, respectively, mean an alkyl group with hydrogen or with 1˜3-carbon.)