A method includes disposing a pair of current-application electrodes in or on a body, including disposing an intrarenal current-application electrode of the pair in a renal artery. Two or more sensing electrodes are disposed in or on the body, including disposing one of the sensing electrodes on en external surface of skin. Control circuitry is activated to (a) apply an electrical current between the pair of current-application electrodes, (b) while applying the electrical current, sense an electrical signal between the sensing electrodes, including the sensing electrode disposed on the external surface of the skin, and (c) based on the electrical signal, ascertain a level of contact between the intrarenal current-application electrode and a wall of the renal artery. In response to the level of contact being less than a threshold level of contact, a disposition of the intrarenal current-application electrode in the renal artery is adjusted.