EWHA UNIVERSITY - INDUSTRY COLLABORATION FOUNDATION;이화여자대학교 산학협력단
发明人:
LEE, Kong Joo,이공주,LEE, Hee-Yoon,이희윤,LEE, Je Jin,이제진,SEO, Eun-Kyoung,서은경,LEE, Eun Sun,이은선,KIM, Hwang Suk,김황석,LEE, Hongsoo,이홍수
申请号：
KRKR2018/005036
公开号：
WO2018/199727A1
申请日:
2018.04.30
申请国别(地区):
KR
年份:
2018
代理人:
摘要：
The present invention relates to a pharmaceutical composition for inhibiting cancer metastasis, the pharmaceutical composition containing an activator compound of the cancer metastasis inhibitor Nm23, a stereoisomer thereof, or a pharmaceutically acceptable salt thereof, as an active ingredient. The compound according to the present invention inhibits the metastasis of cancer cells by stimulating the activity of Nm23 associated with cancer metastasis, and thus can be favorably used as a pharmaceutical composition for inhibiting cancer metastasis.La présente invention concerne une composition pharmaceutique permettant d'inhiber la métastase cancéreuse, la composition pharmaceutique contenant en tant que principe actif un composé activateur de l'inhibiteur de la métastase cancéreuse Nm23, un stéréoisomère de celui-ci, ou un sel pharmaceutiquement acceptable de celui-ci. Le composé selon la présente invention inhibe la métastase de cellules cancéreuses par stimulation de l'activité de Nm23, qui est associée à la métastase cancéreuse, et peut donc être avantageusement utilisé en tant que composition pharmaceutique visant à inhiber la métastase cancéreuse.본 발명은 암 전이 억제인자 Nm23의 활성제 화합물, 이의 입체이성질체 또는 이의 약제학적으로 허용 가능한 염을 유효성분으로 포함하는 암 전이 억제용 약학적 조성물에 관한 것으로, 본 발명에 따른 화합물은 암 전이와 관련된 Nm23의 활성을 증진시킴으로써, 암 세포 전이를 억제하여 암 전이 억제용 약학적 조성물로 유용하게 사용될 수 있다.
