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Cyclohexyl carbamate compounds as skin and/or hair lightening actives
专利权人:
Nicole Titze;Heiko Oertling;Rahim Brodhage;Gabriele Vielhaber;Claudia Gömann
发明人:
Gabriele Vielhaber,Heiko Oertling,Nicole Titze,Claudia Gömann,Rahim Brodhage
申请号:
US13699494
公开号:
US09072676B2
申请日:
2010.05.25
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The present invention relates to the cosmetic, dermatological or therapeutic use of certain cyclohexyl carbamate compounds of formula (I) given below, preferably as skin and/or hair lightening (whitening) actives. The invention further relates to compositions and cosmetic, dermatological or therapeutic products comprising one or more compounds of formula (I) suitable for lightening human skin and/or hair and corresponding methods. The invention further relates to compounds of formula (I) as a drug, their use for the preparation of a pharmaceutical composition for lightening human skin and/or hair and to novel compounds of formula (I)wherein A denoteswherein X, Y and Z independently of one another denote hydrogen, C1-C4-alkyl or C2-C4 -alkenyl,wherein optionally two of the radicals X, Y and Z are covalently bonded to one another under formation of a bicyclic ring system, in such a bicyclic ring system two of the radicals X, Y and Z together preferably form a radical having 1 to 4 carbon atoms, preferably a hydrocarbon radical having 1 to 3 carbon atoms,B denotes NR1R2, whereinR1 denotes hydrogen or an organic radical having 1 to 14 carbon atoms,R2 denotes an organic radical having 1 to 14 carbon atoms, andwherein optionally R1 and R2 are covalently bonded to one another, preferably so that B is a 3 to 8 membered ring.
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