Method for inhibiting cellular activation by insulin-like growth factor-1

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专利权人:

The University of North Carolina at Chapel Hill

发明人:

Clemmons, David R.,Maile, Laura A.

申请号：

AU2012300314

公开号：

AU2012300314A1

申请日:

2012.08.24

申请国别(地区):

AU

年份:

2014

代理人:

摘要：

A method of inhibiting cellular activation by Insulin-like Growth Factor-1 (IGF-1) in a subject in need thereof (e.g., a subject afflicted with cancer, atherosclerosis, diabetic retinopathy or other disease) comprises administering an antagonist that inhibits the binding of IAP to SHPS-1 to the subject in an amount effective to inhibit cellular activation by IGF-1. Compounds and compositions for carrying out such methods are also described.

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