Methods and systems may provide for cognitive decline prediction orassessment. Baseline and follow-up inertial sensor data may be received fromone ormore inertial sensors attached to a person. Baseline and follow-up dataindicative ofcognitive decline may be received from the person. An indication of cognitivedeclinemay be determined based on the baseline and follow-up cognitive decline data.Aclassifier function for predicting cognitive decline may be trained with thebaselineinertial sensor data and the indication of cognitive decline. A classifierfunction forassessing cognitive decline may be trained with the baseline inertial sensordata, adifference between the baseline inertial sensor data and follow-up inertialsensor data,and the indication of cognitive decline.