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Spojina imidazodiazepina
专利权人:
Astellas Pharma Inc.
发明人:
KAWAKAMI Shimpei,IMAIZUMI Tomoyoshi,MASUDA Naoyuki,KUNIKAWA Shigeki,MORITA Masataka,YARIMIZU Junko
申请号:
SI201630411
公开号:
SI3312181T1
申请日:
2016.06.17
申请国别(地区):
SI
年份:
2020
代理人:
摘要:
[Problem] Provided is a compound which is useful as a dopamine D1 receptor positive allosteric modulator (D1 PAM). [Means for Solution] The present inventors have studied a compound which has a positive allosteric modulating action (PAM action) on a dopamine D1 receptor and which can be used as an active ingredient of a pharmaceutical composition for preventing and/or treating cognitive impairment, schizophrenia negative symptom, CIAS, Parkinson's disease, Alzheimer's disease, Huntington's disease, depression, ADHD, drug dependency, or the like. Thus, they have found that the imidazodiazepine compound of the present invention has a PAM action on a dopamine D1 receptor, and thereby completed the present invention. The imidazodiazepine compound of the present invention has a PAM action on a dopamine D1 receptor, and is expected to be an agent for preventing and/or treating cognitive impairment, schizophrenia negative symptom, CIAS, Parkinson's disease, Alzheimer's disease, Huntington's disease, depression, ADHD, drug dependency, or the like.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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