Innovative food supplement based on biological lycopene, which is the bulkproduct, i.e. the total extract, obtainedby treating with supercritical carbon dioxide a suitable extraction matrix,made by 50% biological tomato berries and 50% biologicaldry fruits (almonds, nuts and the like) and/or other components, following aco-extractive technology. Tomato berries are conve-nientlyde-hydrated, milled and riddled; the co-extraction matrix (dry fruits,vegetables, others) is conveniently de-hydrated and milled.The obtained total extract is directly used for preparing lycopene based foodsupplement s, without any modification or ad-ditivation.With respect to the known commercial food supplement, based on lycopene, suchbiological lycopene has unique qualityfeatures: the total extract is 100% natural; absence of chemical solvents;lycopene concentration in the final natural formula (notartificial); absence dosing problems and contra-indications. In the finalproduct, lycopene is mixed with other natural anti-oxidants,co-extracted from the used vegetables. The boxing up of the bulk product(total extract) is made in soft or hard caps in several shapesand colours or in tablets or in other way (e.g. liquid, others).