The Brigham and Women`s Hospital, Inc.;Genzyme Corporation
发明人:
Sergio Pablo Sardi,Clemens Scherzer
申请号:
US16088031
公开号:
US20200124624A1
申请日:
2017.03.24
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Provided herein are methods of determining the efficacy of a treatment for a proteopathy, diagnosing a proteopathy in a subject, determining a subject's risk of developing a proteopathy, determining the stage of a proteopathy in a subject, monitoring a proteopathy in a subject, selecting a treatment for a proteopathy for a subject, and selecting a subject for a clinical trial that include determining a level of at least one sphingolipid in a sample including a biological fluid from the subject.