Treatment of bleeding with low half-life fibrinogen

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专利权人:

Frank Pieper

发明人:

Frank Pieper,Anurag Relan,Erik Jordahl Forsberg

申请号：

US12990643

公开号：

US08557773B2

申请日:

2009.04.29

申请国别(地区):

US

年份:

2013

代理人:

摘要：

The invention provides low-half life fibrinogen with reduced sialyation as a result of recombinant expression or enzymatic and chemical removal. The low-half life fibrinogen is useful in treating or effecting prophylaxis of bleeding particularly in situations of an acute nature in which a high initial dose and rapid decline to normal or below normal levels is desirable.

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