[0081] The present invention relates to an attenuated strain of Salmonella comprising at least one copy of a DNA molecule comprising an expression cassette encoding a VEGF receptor protein for use in cancer immunotherapy, wherein the cancer is characterized by VEGF receptor protein expressing cancer cells. The present invention further relates to an attenuated strain of Salmonella comprising at least one copy of a DNA molecule comprising an expression cassette encoding a VEGF receptor protein for use in cancer immunotherapy, wherein the cancer is characterized by VEGF receptor protein expressing cancer cells, and wherein the cancer is selected from the group consisting of glioblastoma, carcinoid cancer, kidney cancer, particularly renal cell carcinoma, thyroid cancer, lung cancer, particularly Non-Small Cell Lung Cancer (NSCLC), breast cancer, ovarian cancer, prostate cancer, gastrointestinal cancer, particularly colorectal cancer, more particularly colon cancer, and skin cancer, particularly melanoma. The present invention further relates to an attenuated strain of Salmonella comprising at least one copy of a DNA molecule comprising an expression cassette encoding a VEGF receptor protein for use in cancer immunotherapy in a patient comprising at least one VEGF receptor protein expressing cancer cell.La presente invención se refiere a una cepa atenuada de Salmonella que comprende al menos una copia de una molécula de ADN que comprende un casete de expresión que codifica un receptor proteico del VEGF para su uso en inmunoterapia del cáncer, en el que el cáncer se caracteriza por células cancerosas que expresan un receptor proteico del VEGF. La presente invención se refiere adicionalmente a una cepa atenuada de Salmonella que comprende al menos una copia de una molécula de ADN que comprende un casete de expresión que codifica un receptor proteico del VEGF para su uso en inmunoterapia del cáncer, en el que el cáncer se caracteriza por células cancerosas que expresan el
