To search for useful components contained in the rhizome of a calanthe and provide a method for utilizing the useful components found in this way.SOLUTION: Useful components contained in the rhizome of a calanthe are extracted to obtain a plurality of compounds. Of these compounds, one or a plurality of glucoindican and calanthoside having a human hair papilla cell proliferation effect is used as an active ingredient to prepare a composition for proliferation of human hair papilla cells.SELECTED DRAWING: Figure 3【課題】エビネの根茎に含まれる有用成分のさらなる探索、並びに見い出された有用成分の活用方法の提供。【解決手段】エビネの根茎に含まれる有用成分として、複数の化合物が抽出され、これらの化合物のうち、ヒト毛乳頭細胞増殖効果を有するglucoindican並びにcalanthosideのいずれか又は複数を有効成分とすることを特徴とする、ヒト毛乳頭細胞増殖用組成物。【選択図】図３
