The present disclosure relates generally to compositions comprising an antibody such as a monoclonal, chimeric, humanized antibody, antibody fragment etc. that specifically binds to a TREM1 protein, such as a mammalian TREM1 or human TREM1, and an individual in need thereof Use of such compositions in preventing, reducing or treating the risk of [Selected figure] Figure 6D本開示は、一般に、TREM1タンパク質、例えば、哺乳動物TREM1又はヒト TREM1と特異的に結合する、抗体、例えば、モノクローナル、キメラ、ヒト化抗体、抗体断片等を含む組成物及びそれを必要とする個体のリスクの防止、低減又はその治療におけるこのような組成物の使用を対象とする。【選択図】図6D