11.beta.-Halogenem substituované steroidy, kterými jsou 11.beta.-fluor-17.beta.-hydroxy-7.alfa.-methyl-estr-4-en-3-on, 11.beta.-chlor-17.beta.-hydroxy-7.alfa.-methyl-estr-4-en-3-on, 11.beta.-fluor-17.beta.-heptanoyloxy-7.alfa.-methyl-estr-4-en-3-on a 11.beta.-fluor-17.beta.-hydroxy-7.alfa.-methyl-estr-5(10)-en-3-on, použití techto steroidu pro výrobu farmaceutických cinidel a farmaceutická kompozice obsahující alespon jeden takový steroid.In the present invention, there are disclosed 11beta-halosubstituted steroids, which are 11{beta}-fluoro-17{beta}-hydroxy-7{alpha}-methyl-estr-4-en-3-one, 11{beta}-chloro-17{beta}-hydroxy-7{alpha}-methyl-estr-4-en-3-one, 11{beta}-fluoro-17{beta}-heptanoyloxy-7{alpha}-methyl-estr-4-en-3-one and 11{beta}-fluoro-17{beta}-hydroxy-7{alpha}-methyl-estr-5(10)-en-3-one, use of these steroids in the preparation of pharmaceutical agents, and pharmaceutical composition comprising at least one such steroid.