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11beta-Halogenem substituované steroidy, použití techto steroidu a farmaceutická kompozice tyto steroidy obsahující
专利权人:
SCHERING AKTIENGESELLSCHAFT
发明人:
BOHLMANN ROLF,KUENZER HERMANN,NUBBEMEYER REINHARD,ZOPF DIETER
申请号:
CZ20032006
公开号:
CZ303553B6
申请日:
2002.01.24
申请国别(地区):
CZ
年份:
2012
代理人:
摘要:
11.beta.-Halogenem substituované steroidy, kterými jsou 11.beta.-fluor-17.beta.-hydroxy-7.alfa.-methyl-estr-4-en-3-on, 11.beta.-chlor-17.beta.-hydroxy-7.alfa.-methyl-estr-4-en-3-on, 11.beta.-fluor-17.beta.-heptanoyloxy-7.alfa.-methyl-estr-4-en-3-on a 11.beta.-fluor-17.beta.-hydroxy-7.alfa.-methyl-estr-5(10)-en-3-on, použití techto steroidu pro výrobu farmaceutických cinidel a farmaceutická kompozice obsahující alespon jeden takový steroid.In the present invention, there are disclosed 11beta-halosubstituted steroids, which are 11{beta}-fluoro-17{beta}-hydroxy-7{alpha}-methyl-estr-4-en-3-one, 11{beta}-chloro-17{beta}-hydroxy-7{alpha}-methyl-estr-4-en-3-one, 11{beta}-fluoro-17{beta}-heptanoyloxy-7{alpha}-methyl-estr-4-en-3-one and 11{beta}-fluoro-17{beta}-hydroxy-7{alpha}-methyl-estr-5(10)-en-3-one, use of these steroids in the preparation of pharmaceutical agents, and pharmaceutical composition comprising at least one such steroid.
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