PROCESS FOR PRODUCING HIGH PURITY FIBRINOGEN AND THROMBIN FOR FIBRIN SEALANT

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专利权人:

发明人:

ASHOK KUMAR NUVULA,MITALI SAMADDAR,NEELIMA VADDE,ZINIA CHAKRABORTY,SWAPNA SAGAR DUGGINENI,UMA DEVI KOMATH

申请号：

US14883574

公开号：

US20160137719A1

申请日:

2015.10.14

申请国别(地区):

US

年份:

2016

代理人:

摘要：

The present invention relates to a fibrin sealant kit comprising purified fibrinogen and thrombin. The invention particularly relates to an improved chromatographic process for the purification of thrombin and fibrinogen components devoid of any significant plasminogen and other impurities. The absence of plasminogen facilitates the exclusion of a proteolytic inhibitor (aprotinin) from among the kit components.

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