#$%^&*AU2012200865A120120329.pdf#####ABSTRACT The invention relates to methods of treating exudative (wet form) age related macular degeneration (AMD) with VEGF antagonists such as Ranibizumab. The method involves administering to a mammal a number of first individual doses of VEGF antagonist and then administering a number of second individual doses of VEGF antagonist wherein the second individual doses are administered less frequently than the first individual doses.