PRUD'HOMME, Robert K.,PAGELS, Robert F.,MARKWALTER, Chester E.
申请号:
EP16880065
公开号:
EP3393647A4
申请日:
2016.12.21
申请国别(地区):
EP
年份:
2019
代理人:
摘要:
An “inverse” precipitation route to precipitate aqueous soluble species with copolymers as nanoparticles having a hydrophilic, polar core and a less polar shell is described. The aggregation of these nanoparticles to form larger microparticles and monoliths provides a highly loaded construct (e.g., a depot) for the sustained and controlled release of actives.