Said Al-Jaroudi,Muhammad Altaf,Abdulaziz Al-Saadi,Anvarhusein Abdulkadir Isab
申请号:
US15282636
公开号:
US09649292B2
申请日:
2016.09.30
申请国别(地区):
US
年份:
2017
代理人:
摘要:
Gold(III) complexes having mixed ligands as anticancer agents. The gold(III) complexes are coordinated to bidentate ligands having diamino functional groups: a diaminocyclohexane ligand and an ethylenediamine ligand. These complexes can exist in both cis- and trans-configurations. Also described are pharmaceutical compositions incorporating the gold(I) complexes, methods of synthesis, methods of treating cancer and methods of inhibiting cancer cell proliferation and inducing cancer cell apoptosis.