Darryl David Dixon,Jonas Grina,John A. Josey,James P. Rizzi,Stephen T. Schlachter,Eli M. Wallace,Bin Wang,Paul Wehn,Rui Xu,Hanbiao Yang
申请号:
US15556153
公开号:
US10807948B2
申请日:
2016.03.04
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Disclosed herein are substituted indane derivatives useful as HIF-2α inhibitors. Pharmaceutical compositions comprising said indane derivatives and methods of using said indane derivatives for treating proliferative diseases, such as renal cell carcinoma and von Hippel-Lindau disease, and other conditions associated with HIF-2α activity are also disclosed.