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1-Heterocyclylsulfonyl, 3-aminomethyl, 5-(hetero-)aryl substituted 1-H-pyrrole derivatives as acid secretion inhibitors
专利权人:
Takeda Pharmaceutical Company Limited
发明人:
KAJINO, Masahiro,HASUOKA, Atsushi,NISHIDA, Haruyuki
申请号:
AU2015268744
公开号:
AU2015268744A1
申请日:
2015.12.15
申请国别(地区):
AU
年份:
2016
代理人:
摘要:
#$%^&*AU2015268744A120160121.pdf#####Abstract The present invention provides a compound having a superior acid secretion inhibitory effect and showing an antiulcer activity and the like. The present invention provides a compound represented by the formula (1) wherein R1 is a nitrogen-containing monocyclic heterocyclic group optionally condensed with a benzene ring or a heterocycle, the nitrogen-containing monocyclic heterocyclic group optionally condensed with a benzene ring or a heterocycle optionally has substituent(s), R2 is an optionally substituted C614 aryl group, an optionally substituted thienyl group or an optionally substituted pyridyl group, R3 and R4 are each a hydrogen atom, or one of R3 and R4 is a hydrogen atom and the other is an optionally substituted lower alkyl group, an acyl group, a halogen atom, a cyano group or a nitro group, and R5 is an alkyl group or a salt thereof. H~R R C-N H R 4 ~N R R
来源网站:
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来源网址:
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