SCHETTINI, JORGE,HORNUNG, TASSILO,HOLTERMAN, DANIEL,SPETZLER, DAVID
申请号：
CA2892490
公开号：
CA2892490A1
申请日:
2013.11.26
申请国别(地区):
CA
年份:
2014
代理人:
摘要：
Biomarkers can be assessed for diagnostic, therapy-related or prognostic methods to identify phenotypes, such as a condition or disease, or the stage or progression of a disease, select candidate treatment regimens for diseases, conditions, disease stages, and stages of a condition, and to determine treatment efficacy. Circulating biomarkers from a bodily fluid can be used in profiling of physiological states or determining phenotypes. These include nucleic acids, protein, and circulating structures such as vesicles, and nucleic acid-protein complexes. The invention provides methods of assessing microvesicles in a biological sample. The invention also provides an aptamer to a microvesicle surface antigen. The aptamer may be used for therapeutic purposes.
