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SPARC由来の癌拒絶抗原ペプチド及びこれを含む医薬
专利权人:
オンコセラピー・サイエンス株式会社
发明人:
西村 泰治,生田 義明,中鶴 修一
申请号:
JP2008521269
公开号:
JP5150849B2
申请日:
2007.06.15
申请国别(地区):
JP
年份:
2013
代理人:
摘要:
It is an objective of the present invention to identify SPARC protein-derived peptides that are able to induce human killer T cells and helper T cells having cytotoxic activity to tumors, and to provide a means for carrying out a tumor immunotherapy of patients with various types of cancers overexpressing SPARC. The present invention provides a peptide of any of the following: (A) a peptide which consists of the amino acid sequence as shown in any one of SEQ ID NOS: 1 to 3 or (B) a peptide which consists of an amino acid sequence comprising a substitution or addition of one or several amino acids with respect to the peptide consisting of the amino acid sequence as shown in any one of SEQ ID NOS: 1 to 3, and which has capacity to induce cytotoxic (killer) T cells.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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