PROBLEM TO BE SOLVED: To provide a composition having rotavirus infection preventing action.SOLUTION: The composition against infection with rotavirus is a microfiltration retentate of whey, a product obtained by treating whey using centrifugation and/or ammonium sulfate precipitation, or a dehydrated product thereof. The micropore diameter of a microfiltration membrane ranges from 0.004 to 1.4 &mum. The centrifugal force in centrifugation ranges from 300 to 30,000 g. The saturation level in ammonium sulfate precipitation ranges from 30 to 100%. The whey is centrifuged/purified and adjusted to approximately neutral pH (6.8-7.2), and then, treated with the microfiltration membrane. Further, after a process, wherein water is added to the retentate and then the retentate is subjected to microfiltration treatment, is repeated several times (usually three times), the retentate is dehydrated by a conventional method.COPYRIGHT: (C)2012,JPO&INPIT【課題】ロタウィルス感染防御作用を有する組成物の提供。【解決手段】ホエイの精密濾過保持物、遠心分離処理物および/または硫安沈殿処理物またはその乾燥物であって、精密濾過膜の孔径が0.004~1.4μmの範囲にあり、遠心分離処理の重力が300~30,000gの範囲にあり、硫安沈澱の飽和度が30~100%の範囲にある。ホエイを遠心分離/清浄化し、pHを中性付近(6.8~7.2)に調節した後、MF膜処理する。さらに保持液に加水→MF膜処理といった工程を複数回(通常3回)繰り返した後、保持液を常法により乾燥する。【選択図】なし
