A fluid delivery system comprises: a control interface and multiple unique loading guides. The control interface of the fluid delivery system is configured to accept a fluid pump assembly. The multiple loading guides are retractable from the fluid delivery system to retain and control movement of a facing of the fluid pump assembly to contact the control interface on the facing of the fluid delivery system. In one configuration, the control interface is disposed in a cavity of the fluid delivery system; the multiple loading guides are disposed at locations in proximity to the cavity. The multiple loading guides can be configured to slidably retract in unison to support substantially orthogonal insertion of the fluid pump assembly into the cavity of the fluid delivery system.