Mautino, Mario,Kumar, Sanjeev,Jaipuri, Firoz,Waldo, Jesse,Potturi, Hima,Zhuang, Hong
申请号:
NZ73697816
公开号:
NZ736978A
申请日:
2016.06.02
申请国别(地区):
NZ
年份:
2019
代理人:
摘要:
Presently provided are indoximod prodrug and salt compounds and pharmaceutical compositions comprising salts and prodrugs of indoximod, that produce enhanced plasma concentration and exposure to indoximod compared to direct administration of indoximod, in patients in need of treatment of immunosuppression mediated by the indoleamine-2,3-dioxygenase pathway, such as patients with cancer or chronic infectious diseases.