PEPTIDES INHIBITING NEURONAL EXOCYTOSIS, MIXING OF PEPTIDES, COSMETIC AND PHARMACEUTICAL COMPOSITIONS, USE OF A PEPTIDE, AND METHOD FOR COSMETIC TREATMENT IN A HUMAN FACIAL AND / OR FACIAL WRINKLE
ANTONIO FERRER MONTIEL,Anabel Gil Tebar,Clara Blanes Mira,Enrique Perez Paya,GREGORIO FERNÁNDEZ BALLESTER,Luis Miguel Gutiérrez Perez,Mercedes Llobregat Hernández,ROSA PLANELLS CASES,Salvador Viniegra
申请号：
BRPI0011152
公开号：
BRPI0011152B1
申请日:
2000.02.18
申请国别(地区):
BR
年份:
2018
代理人:
摘要：
"neuronic exocytosis inhibitor peptides, cosmetic and pharmaceutical compositions containing them". The peptide has a sequence of 3 to 30 contiguous amino acids from the amino terminus of the snap-25 protein and is useful as a neuronic exocytosis inhibitor. Cosmetic and pharmaceutical compositions comprise said peptide, optionally together with one or more peptides from the carboxy end of snap-25. The compositions are suitable for the treatment of facial wrinkles, facial asymmetry, and pathological disorders and changes mediated by pathological neuronic exocytosis."péptidos inibidores da exocitosis neurónica, composições cosméticas e farmacêuticas que os contêm". o péptido tem uma sequência de 3 a 30 amino-ácidos contíguos procedentes do extremo amino da proteína snap-25 e é útil como inibidor da exocitosis neurónica. as composições cosméticas e farmacêuticas compreendem o mencionado péptido, opcionalmente junto com um ou mais péptidos procedentes do extremo carboxilo da snap-25. as composições são adequadas para o tratamento das rugas faciais, da assimetria facial e de transtornos e alterações patológicas mediadas por uma exócitosis neurónica patológica.
