Neil Graham,Marius Ardeleanu,Allen Radin,Jennifer D. Hamilton,Ariel Teper
申请号:
US14632988
公开号:
US10370449B2
申请日:
2015.02.26
申请国别(地区):
US
年份:
2019
代理人:
摘要:
The present invention provides methods for treating, preventing or ameliorating skin infections, including bacterial and viral infections. In certain embodiments, the invention provides methods to reduce skin infection in a patient with atopic dermatitis (AD). Also provided are methods for improving skin barrier function, and methods for reducing the risk of inflammation due to microbial infection in a patient in need thereof. The methods of the present invention comprise administering to a patient in need thereof a pharmaceutical composition comprising an interleukin-4 receptor (IL-4R) antagonist such as an anti-IL-4R antibody.