The invention relates to an autoinjector (1) comprising: - a housing (30, 30a, 30b), a container movable within said housing between an initial position and an insertion position, said movement being prevented when the container is in its passive state, and permitted when the container is in its active state, and - a safety shield (40) movable with respect to said housing between a first position and a second position, said movement placing the container in its active state, - first retaining means (61, 52) for maintaining said container in its passive state, characterized in that it comprises - first deactivating means (50, 51), capable of rotating with respect to said first retaining means from a first position, in which said first retaining means maintain said container in its passive state, to a second position, in which said first retaining means allow the passage of said container in its active state, said rotation being caused by movement of said safety shield from its first position to its second position under distal pressure exerted on said housing.Linvention porte sur un auto-injecteur (1) comprenant : - un boîtier (30, 30a, 30b), un conteneur mobile à lintérieur dudit boîtier entre une position initiale et une position dintroduction, ledit mouvement étant empêché lorsque le conteneur se situe dans son état passif, et autorisé lorsque le conteneur se situe dans son état actif, et - un écran de sécurité (40) mobile par rapport audit boîtier entre une première position et une seconde position, ledit mouvement plaçant le conteneur dans son état actif, - des premiers moyens de retenue (61, 52) pour retenir ledit conteneur dans son état passif, caractérisé par le fait quil comprend - des premiers moyens de désactivation (50, 51), capables de tourner par rapport auxdits premiers moyens de retenue dune première position, dans laquelle lesdits premiers moyens de retenue retiennent ledit conteneur dans son état passif, à une seconde position, dans laquelle lesdits
