PROBLEM TO BE SOLVED: To provide a new heart disease prevention therapeutic agent that prevents onset and progress of cardiac failure.SOLUTION: The heart disease prevention therapeutic agent, especially cardiac failure prevention therapeutic agent includes nobiletin as an active ingredient. Cardiac failure is accompanied by cardiac muscle cell hypertrophy.COPYRIGHT: (C)2011,JPO&INPIT【課題】本発明の課題は、心不全の発症、進展を防止できる新たな心疾患予防治療剤を提供することにある。【解決手段】ノビレチンを有効成分とする心疾患予防治療剤、特に心不全予防治療剤。【選択図】なし