An apparatus for treatment of tissue within a body requiring thermotherapyincludes a catheter to be inserted into a bodily conduit, an energy-emittingsource disposed within the catheter, a compression balloon surrounding theenergy-emitting source where the compression balloon has an inflated diameterthat is greater than that of the bodily conduit in a relaxed state and anoutside surface of the balloon is coated with one of gene modifiers and drugor medication, and means for activating the energy-emitting source to radiateenergy to heat the drug-coated compression balloon and tissue to be treatedwhereby the heated drug-coated compression balloon effectively delivers theone of the gene modifiers and drug or medication to a target area of thediseased tissue. In addition, methods for using the above apparatus to treatdiseased tissue are disclosed.
