A tissue shredding device is provided which includes a shredding pipe which is inserted into a patient body in which a plurality of opening portions is formed in a longitudinal direction and a plurality of wires which is withdrawn from the opening portion, bent back outside the shredding pipe, and drawn into the shredding pipe. Here, the tissue shredding device may be changed to one of a first arrangement in which the wires are withdrawn from the shredding pipe so that a tissue can be introduced toward top portions corresponding to bent-back parts of the plurality of wires, a second arrangement in which the top portions are arranged opposite to the shredding pipe, and a third arrangement in which the wires are drawn into the opening portion.
