PROBLEM TO BE SOLVED: To provide tablets having small variation of a volume filled into a mortar, as well as small variation of mass or tableting pressure, and to provide production methods thereof.SOLUTION: A tablet of the present invention has a drug-containing layer having both the following component (A) and component (B). A method of producing the tablet of the invention has a tableting step of tableting a mixed powder comprising the following component (A) and component (B) to form a drug-containing layer. Component (A): dried aluminium hydroxide gel whose median diameter is 150 to 400 μm. Component (B): allylisopropylacetylurea whose median diameter is 20 to 100 μm.SELECTED DRAWING: NoneCOPYRIGHT: (C)2018,JPO&INPIT【課題】臼への充填量のバラつきが小さく、質量のバラつきや打錠圧のバラつきが小さい錠剤およびその製造方法の提供。【解決手段】本発明の錠剤は、下記(A)成分と、下記(B)成分とを併有する薬物含有層を備える。本発明の錠剤の製造方法は、下記(A)成分と、下記(B)成分とを含む混合粉体を打錠して薬物含有層を形成する打錠工程を有する。 (A)成分:中位径が150~400μmである乾燥水酸化アルミニウムゲル。 (B)成分:中位径が20~100μmであるアリルイソプロピルアセチル尿素。【選択図】なし
