The present invention provides a pharmaceutical composition effective to provide targeted blood levels effective therapeutically therapeutically active ingredient when administered to the digestive tract. In one embodiment, said pharmaceutical composition, the therapeutically active ingredient an effective amount of water-soluble enhancer one, for example, there are salts of medium chain fatty acids or medium chain fatty acid, ester, ether or a derivative of at least a therapeutically , an enhancer having a carbon chain length of from about 20 to about 4 carbon atoms, I and a sugar.本発明は、消化管に投与すると治療活性成分の治療上効果的な血中レベルを対象にもたらすのに効果的な医薬組成物を提供する。一態様では、前記医薬組成物が、治療上効果的な量の治療活性成分と、少なくとも1種の水溶性増強剤、例えば、中鎖脂肪酸または中鎖脂肪酸の塩、エステル、エーテルもしくは誘導体であり、炭素原子約4個から約20個の炭素鎖長を有する増強剤と、糖とを含む。
