The present invention relates to an ICT convergence smart pen management system having a mist spray system for spraying a mixed liquid of water and chemicals into a pen using a plurality of spray nozzles. The ICT convergence smart pen management system having a mist spray system of the present invention comprises: an automatic administration device for supplying a diluted drug； a water tank for storing first water supplied from outside； a pressurization pump for applying pressure to the first water stored in the water tank and supplying the same； a filtering device for passing the first water supplied from the pressurization pump to filter the same； a mixing unit for mixing the first water supplied from the filtering device and the drug supplied from the automatic administration device； a high-pressure pump for applying a constant pressure to a mixed liquid of the water and the drug discharged from the mixing unit, and supplying the same into a pen； a mixed liquid transfer pipe for transferring a mixed liquid supplied from the high-pressure pump to a space inside the pen； a spray nozzle provided in the mixed liquid transfer pipe to spray the mixed liquid； a sensing unit for measuring humidity and temperature inside and outside the pen and the quality of air inside the pen； a pen environment adjustment unit for controlling the temperature, humidity, and ventilation in the pen； and a control unit for receiving data from the sensing unit to control the pen environment adjustment unit to improve a pen environment, and controlling a dilution concentration of the automatic administration device to supply and control the mixed liquid.복수의 분무노즐을 이용하여 물과 약품이 혼합된 혼합액을 축사내로 분무하는 안개분무 시스템으로서, 본 발명에 따른 안개분무 시스템을 구비하는 ICT 융복합 스마트 축사관리 시스템은 희석된 약물을 공급하는 자동투약장치； 외부로부터 공급되는 제1 물이 저장되는 물탱크； 상기 물탱크에 저장된 제1 물에 압력을 가하여 공급하는 가압펌프； 상기 가압펌프로부터 공급되는 제1 물이 통과하면서 여과되는 여과장치； 상기 여과장치로부터 공급되는 제1 물과 상기 자동투약장치로부터 공급되는 약물이 혼합되는 혼합부； 상기 혼압부로부터 배출되는 상기 물과 상기 약물의 혼합액에 일정한 압력을 가하여 상기 축사 내로 공급하는 고압펌프； 상기
