A smart keyboard with physiological signal detection capability includes: a keyboard body, a palm rest, a sensing module, a physiological signal detection module, and a processing module. The sensing module is disposed on the palm rest to sense whether a palm of a user is placed on the palm rest and generate a sensing signal. The physiological signal detection module is disposed on the palm rest to detect a physiological characteristic of the user to generate a physiological signal. The processing module is electrically connected to the sensing module and the physiological signal detection module. The processing module is configured to drive the physiological signal detection module for activating detection means when the palm rest is touched by the user and deactivating detection means when the user palm does not touch the palm rest, and to output a warning signal when the physiological characteristic of the user is abnormal according to the physiological signal.一種具生理監測功能的智能鍵盤，包括：一鍵盤本體、一掌托件、一手掌感測模組、一生理監測模組、及一處理模組。手掌感測模組配置於掌托件上，用以感測使用者的手掌是否放在掌托件上，並產生一手掌感測信號。生理監測模組配置於掌托件上，用以監測使用者的生理特徵以產生一生理信號。處理模組電性連接於手掌感測模組及生理監測模組，用以根據手掌感測信號判斷出掌托件被使用者觸碰時控制生理監測模組啟動監測，而在判斷出掌托件未被使用者觸碰時控制生理監測模組關閉監測，並用以根據生理信號判斷出使用者的生理特徵異常時輸出一警示信號。
