Stefanie GRABULOVSKI,Titus KRETZSCHMAR,Simone SCHMITT,Abdijapar SHAMSHIEV,Thorsten Alexander SCHAFER
申请号:
US15202982
公开号:
US20170051054A1
申请日:
2016.07.06
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The present invention relates to anti-IL-1 beta binding members and in particular to monovalent high potency IL-1 beta-binding antibody fragments being highly stable and soluble. Such binding members may be used in the treatment of inflammatory and other diseases as well as in diagnostics. Also provided are related nucleic acids, vectors, cells, and compositions.