HUANG, CHING JANG,黄青真,黃青真,PAI, YI PING,白依平,白依平,HUANG, TING NI,黄婷妮,黃婷妮
申请号：
TW102105095
公开号：
TW201431549A
申请日:
2013.02.08
申请国别(地区):
TW
年份:
2014
代理人:
摘要：
The present invention provides a use of a bitter compound for the manufacture of a medicament for the treatment of enhancing the secretion of GLP-1 from intestinal endocrine L-cells, and the bitter compound is cucurbitane-triterpenoid or allyl isothiocyanate. The bitter compound can regulate the secretion of GLP-1, thus is potentially reliable for the development of medicament or healthy victual.本發明係關於一種苦味化合物在製備活化腸道內分泌細胞分泌GLP-1之藥物的用途,其中該苦味化合物係為葫蘆烷型三萜類化合物或異硫氰酸丙烯酯(allyl isothiocyanate)。藉由本發明之苦味化合物在製備活化腸道內分泌細胞分泌GLP-1之藥物的用途可有效促進腸道內分泌L細胞分泌GLP-1,可提供作為一種醫藥組成物或保健食品成份。
