TESCHNER, WOLFGANG,SCHWARZ, HANS-PETER,MADLENER, RUTH,SVATOS, SONJA,PLJEVLJAKOVIC, AZRA,WEBER, ALFRED
申请号:
MYPI 2012005078
公开号:
MY161617A
申请日:
2011.05.26
申请国别(地区):
MY
年份:
2017
代理人:
摘要:
THE PRESENT INVENTION PROVIDES NOVEL METHODS FOR REDUCING THE SERINE PROTEASE AND/OR SERINE PROTEASE ZYMOGEN CONTENT OF A PLASMA-DERIVED PROTEIN COMPOSITION. ALSO PROVIDED ARE METHODS FOR MANUFACTURING PLASMA-DERIVED PROTEIN COMPOSITIONS HAVING REDUCED SERINE PROTEASE AND OR SERINE PROTEASE ZYMOGEN CONTENT. AMONG YET OTHER ASPECTS, THE PRESENT INVENTION PROVIDES AQUEOUS AND LYOPHILIZED COMPOSITIONS OF PLASMA-DERIVED PROTEINS HAVING REDUCED SERINE PROTEASE AND/OR SERINE PROTEASE ZYMOGEN CONTENT. YET OTHER ASPECTS INCLUDE METHODS FOR TREATING, MANAGING, AND/OR PREVENTING A DISEASE COMPRISING THE ADMINISTRATION OF A PLASMA-DERIVED PROTEIN COMPOSITION HAVING A REDUCED SERINE PROTEASE OR SERINE PROTEASE ZYMOGEN CONTENT. FIGURE 3