Michael Otto BARDROFF,Tina BUCH,Christian GRAF,Daniel HEITMANN,Thomas JOSTOCK,Hans-Peter KNOPF,Rolf KOEHLER,Jiri KOVARIK,Stephen John OLIVER,Dhavalkumar PATEL,Maximilian WOISETSCHLAEGER
申请号：
US16844999
公开号：
US20200308309A1
申请日:
2020.04.09
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The invention relates to bivalent bispecific monoclonal antibodies (bbmAb) or variants thereof, and methods of manufacturing such antibodies by co-expressing modified Fc-mutated derivatives of two different monoclonal antibodies in mammalian cell lines.
