JURE-KUNKEL MARIA,HEFTA LAURA J.,SANTORO MARC,GANGULY SUBINAY,HALK EDWARD L.,JURE-KUNKEL Maria,HEFTA Laura J.,SANTORO Marc,GANGULY Subinay,HALK Edward L.
申请号:
SI200432112
公开号:
SI1670828T1
申请日:
2004.10.12
申请国别(地区):
SI
年份:
2014
代理人:
摘要:
Fully human antibodies and antigen-binding portions thereof that bind to human 4-1BB and that allow binding of human 4-1BB to a human 4-1BB ligand. In one aspect, the antibody is an IgG4 antibody. Also provided is a method for treating a disease in a subject comprising administering a therapeutically effective amount of the antibody to said subject.