您的位置: 首页 > 农业专利 > 详情页

FORMULACION TOPICA PARA UN INHIBIDOR DE JAK
专利权人:
INCYTE CORPORATION
发明人:
PARIKH, BHAVNISH,SHAH, BHAVESH,YELESWARAM, KRISHNASWAMY
申请号:
PE0021972012
公开号:
PE02162013A1
申请日:
2011.05.20
申请国别(地区):
PE
年份:
2013
代理人:
摘要:
Refers to a Pharmaceutical formulation comprising: a) an oil in water emulsion, which comprises: (i) water in an amount of 35% to 65% by weight of the formulation, (ii) a component such as Jellies, Oily, Fatty alcohol, mineral oils, among others, in a quantity of 10% to 40%. Weight of the formulation.(iii) a component and Emulsifier as Fatty esters and Fatty Esters of sorbitan monopalmitate, in an amount of 1% to 9% by weight of the formulation and (b) a Therapeutic Agent as (R) - 3-cyclopentyl-3 - [4 - (7H pyrrolo [2,3-d] pyrimidine - 4-yl) - 1H pyrazol-1-yl] propanenitrile, in an amount of 0.5% to 1.5% in weight of the formulation with respect to the Free Base also includes a Stabilizing Agent such as polysaccharides, in an amount of 0.05% to 5% by weight of the formulation, a Solvent Component as alquilenglicoles and polialquilenglicoles in an amount of 10% to 35% by weight of the formulation, a component such as alquilparabenos antimicrobial Preservative Phenoxyethanol and in an amount of 0.05% to 3% by weight of the formula Tion and a chelating Agent such as disodium edetate.This formulation is useful for the treatment of Skin Disorders such as atopic dermatitis and psoriasisSE REFIERE A UNA FORMULACION FARMACEUTICA QUE COMPRENDE: A) UNA EMULSION DE ACEITE EN AGUA, QUE COMPRENDE: i) AGUA, EN UNA CANTIDAD DE 35% A 65 % EN PESO DE LA FORMULACION, ii) UN COMPONENTE OLEOSO TAL COMO, VASELINAS, ALCOHOLES GRASOS, ACEITES MINERALES, ENTRE OTROS, EN UNA CANTIDAD DE 10% A 40 % EN PESO DE LA FORMULACION, Y iii) UN COMPONENTE EMULSIONANTE TAL COMO ESTERES GRASOS DE GLICERILO Y ESTERES GRASOS DE SORBITAN, EN UNA CANTIDAD DE 1% A 9 % EN PESO DE LA FORMULACION Y B) UN AGENTE TERAPEUTICO TAL COMO (R)-3-CICLOPENTIL-3-[4-(7H-PIRROLO[2,3-d]PIRIMIDIN-4-IL)-1H-PIRAZOL-1-IL]PROPANONITRILO, EN UNA CANTIDAD DE 0.5% A 1.5 % EN PESO DE LA FORMULACION CON RESPECTO A LA BASE LIBRE ADEMAS COMPRENDE UN AGENTE ESTABILIZANTE TAL COMO POLISACARIDOS, EN UNA CANTIDAD DE 0.05% A 5 % EN PESO DE L
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

意 见 箱

匿名:登录

个人用户登录

找回密码

第三方账号登录

忘记密码

个人用户注册

必须为有效邮箱
6~16位数字与字母组合
6~16位数字与字母组合
请输入正确的手机号码

信息补充